Contribution of NADH Oxidase to Aerobic Metabolism of Streptococcus pyogenes
نویسندگان
چکیده
منابع مشابه
Contribution of NADH oxidase to aerobic metabolism of Streptococcus pyogenes.
An understanding of how the heme-deficient gram-positive bacterium Streptococcus pyogenes establishes infections in O(2)-rich environments requires careful analysis of the gene products important in aerobic metabolism. NADH oxidase (NOXase) is a unique flavoprotein of S. pyogenes and other lactic acid bacteria which directly catalyzes the four-electron reduction of O(2) to H(2)O. To elucidate a...
متن کاملContribution of glutathione peroxidase to the virulence of Streptococcus pyogenes.
Glutathione peroxidases are widespread among eukaryotic organisms and function as a major defense against hydrogen peroxide and organic peroxides. However, glutathione peroxidases are not well studied among prokaryotic organisms and have not previously been shown to promote bacterial virulence. Recently, a gene with homology to glutathione peroxidase was shown to contribute to the antioxidant d...
متن کاملAerobic metabolism of Streptococcus agalactiae.
Streptococcus agalactiae cultures possess an aerobic pathway for glucose oxidation that is strongly inhibited by cyanide. The products of glucose oxidation by aerobically grown cells of S. agalactiae 50 are lactic and acetic acids, acetylmethylcarbinol, and carbon dioxide. Glucose degradation products by aerobically grown cells, as percentage of glucose carbon, were 52 to 61% lactic acid, 20 to...
متن کاملGlucose and galactose metabolism in Streptococcus pyogenes.
Studies initially concerned with the role of nutrient carbohydrates in the formation of capsular hyaluronic acid by various strains of Streptococcus pyogenes led to the finding that the end products of glucose and galactose dissimilation in these organisms differ quantitatively (Steele et al., 1954). This paper is a report of further investigations on the latter aspect of the carbohydrate metab...
متن کاملHydrogen peroxide production in Streptococcus pyogenes: involvement of lactate oxidase and coupling with aerobic utilization of lactate.
Streptococcus pyogenes strains can be divided into two classes, one capable and the other incapable of producing H2O2 (M. Saito, S. Ohga, M. Endoh, H. Nakayama, Y. Mizunoe, T. Hara, and S. Yoshida, Microbiology 147:2469-2477, 2001). In the present study, this dichotomy was shown to parallel the presence or absence of H2O2-producing lactate oxidase activity in permeabilized cells. Both lactate o...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Bacteriology
سال: 2000
ISSN: 0021-9193,1098-5530
DOI: 10.1128/jb.182.2.448-455.2000